Thursday 26 May 2016

Case Studies in Biomedical Research Ethics (Basic Bioethics)

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Case Studies in Biomedical Research Ethics (Basic Bioethics)

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Case Studies in Biomedical Research Ethics (Basic Bioethics) Description

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This textbook for instruction in biomedical research ethics can also serve as a valuable reference for professionals in the field of bioethics. The 149 cases included in the book are grouped in nine chapters, each of which covers a key area of debate in the field. Some of the case studies are classics, including the famous cases of the Tuskegee Syphilis Study (in which subjects with syphilis were not given treatment) and the Willowbrook hepatitis studies (in which institutionalized subjects were intentionally exposed to hepatitis). Others focus on such current issues as human embryonic stem cell research, cloning by somatic nuclear transfer, and the design and function of institutional review boards. Each chapter begins with a brief introduction that places the issues raised in context; this is followed by a number of cases (each of which is no more than a few pages). Study questions meant to encourage further discussion follow each case.After an introductory discussion of the history and tenets of ethics in medical research, the book's chapters cover the topics of oversight and study design; informed consent; the selection of subjects; conflicts of interest; the social effects of research; embryos, fetuses, and children; genetic research; the use of animals; and authorship and publication. Following these chapters are appendixes with the texts of the Nuremburg Code and the World Declaration of Geneva, two key documents in the establishment of bioethical standards for research. Also included are a glossary, a table of cases by general category, and an alphabetical listing of cases.

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Friday 20 May 2016

Sharks Get Cancer, Mole Rats Don't: How Animals Could Hold the Key to Unlocking Cancer Immunity in Humans

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Sharks Get Cancer, Mole Rats Don't: How Animals Could Hold the Key to Unlocking Cancer Immunity in Humans Info

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This fresh and fascinating exploration of new directions in cancer research focuses on the important role of the immune system in combatting this dread disease. Integrating clues from the animal kingdom, the veterinary clinic, extraordinary human cases, and even embryology, the author—a cancer physician, biologist, and physicist—creates a novel and compelling account of tumor immunology and the promises of immunotherapy.

As the author explains, animals offer us many tantalizing clues about the nature of cancer in humans. Tasmanian devils are on the verge of extinction due to a virulent form of contagious cancer; soft-shelled clams on the East coast of North America are vanishing due to another epidemic of contagious cancer; dogs also contract a contagious cancer but they spontaneously overcome it; and a type of mouse and the homely mole rat are not susceptible to the disease at all. 

In humans, there are rare instances of spontaneous cures of advanced cancers induced by radiation. An uncommon form of dwarfism called Laron syndrome confers total cancer immunity on the people who inherit the condition. And recent research suggests that cancer has stolen the secret that shields the embryo against hostile attacks from the mother’s immune system.

The author makes a convincing case that what all of these diverse examples have in common is the immune system and its ability or inability to respond to malignancies. He concludes with a review of the exciting research on the human immune system and the development of new treatments that are inducing the immune system to combat and conquer even the deadliest cancers..


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Wednesday 18 May 2016

Curbside Consultation in Glaucoma: 49 Clinical Questions

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Curbside Consultation in Glaucoma: 49 Clinical Questions Description

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Are you looking for concise, practical answers to those questions that are often left unanswered by traditional glaucoma references? Are you seeking brief, evidence-based advice for common clinical dilemmas? Curbside Consultation in Glaucoma: 49 Clinical Questions provides quick and direct answers to the thorny questions most commonly posed during a “curbside consultation” between glaucoma specialists.

Dr. Dale K. Heuer, and associate editors Dr. Steven J. Gedde and Dr. Richard Lewis, have designed this unique reference in which top glaucoma specialists offer expert advice, preferences, and opinions on tough clinical questions commonly associated with the day-to-day diagnosis and care of glaucoma patients. The unique Q&A format provides quick access to current information related to glaucoma with the simplicity of a conversation between two colleagues. Numerous images, diagrams, and references are included to enhance the text and to illustrate glaucoma pearls.

Curbside Consultation in Glaucoma: 49 Clinical Questions provides information basic enough for residents while also incorporating expert pearls that even high-volume glaucoma specialists will appreciate. General practitioners, residents, fellows, and optometrists alike will benefit from the user-friendly and casual format and the expert advice contained within.

Some of the questions that are answered:
• Which imagining device should I use in my practice?
• How should I set a target intraocular pressure?
• What is “maximum medical therapy” for glaucoma now?
• Which glaucoma medications may be used safely during pregnancy? In children?
• Is selective laser trabeculoplasty better than argon or diode laser trabeculoplasty?
• Which of the new incisional surgical alternatives to trabeculectomy should I consider for my patients? In what clinical settings should I consider them?
• In which patients with glaucoma and cataract should I perform a combined
procedure? Cataract surgery alone? Trabeculectomy first?



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Tuesday 17 May 2016

Essentials of Low Vision Practice, 1e

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Essentials of Low Vision Practice, 1e

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Essentials of Low Vision Practice, 1e Info

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In Essentials of Low Vision Practice, Dr. Brilliant and a group of expert contributors explore how clinical data obtained from patient observation, history and examination procedures can be integrated into an effective treatment and rehabilitation plan. Each chapter examines how to evaluate a patient and how to follow through with treatment options..


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Primer of Biostatistics

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Primer of Biostatistics

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Primer of Biostatistics Description

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You'll start with the basics, including analysis of variance and the t test, then advance to a multiple comparison testing, contingency tables, regression, and more. Examples from the current literature illustrate key concepts throughout.
New:
* More on multiple comparison testing, including the Holm test
* Discussion of relative risks and odds ratios
* Updated examples from the literature.


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Sunday 8 May 2016

SIA Analysis: A step by step approach

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SIA Analysis: A step by step approach

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SIA Analysis: A step by step approach Description

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In the extremely demanding world of modern ophthalmic surgery, the importance of Surgically Induced Astigmatism cannot be overemphasized. This delightful little book is a step by step guide that unravels the processes behind vector analysis, Cartesian coordinates, and aggregate data analysis.

The concepts are clearly and practically explained. A number of examples along the way reinforce the learning process, and allow the reader to cross-check calculations.

The book ends with a chapter on the free software available on the web, describing the various versions, and where to download them from.

A must read for anyone wanting to understand SIA analysis..


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